The Laboratory, headed by Dr. Paul Mischel, aims to transform the care of patients with glioblastoma, the most common form of brain cancer in adults, through molecular medicine. We use quantitative molecular approaches to study and understand the signaling networks that are altered in cancer cells in culture, in relevant in vivo cancer model systems and most importantly in human cancer patients. We have developed, and continue to develop, a suite of approaches for studying glioblastoma patients in state-of-the-art, moleculary guided clinical trials, with the goal of using this information to develop more effective, less toxic therapies. Our laboratory is patient-focused and greatly values interdisciplinary collaboration.

Molecular Pathology